Joe

Posts by Joe:

Summary

Joe is the Director of Product at Ometa Labs LLC, where he works on developing tools for mass spectrometry. Joe recieved his Bachelors and Masters degrees at UNC Greensboro under the training of Dr. Nadja Cech and completed his PhD in Chemistry at Simon Fraser University with Dr. Roger Linington working in NMR Metabolomics. While at SFU, Joe was awarded and funded by the NIH F31 fellowship.

Joe has worked in natural products for over a decade, working with botanical, fungal, and bacterial sources. He has training in microbial and fungal cultivation, compound isolation and characterization, biological assay development, and metabolomics data analysis. After completing his PhD, Joe moved into software development and machine learning where he applies his previous experience to design user-focused tools for complex datasets.

Joe enjoys fishing, playing live music, and riding his motorcycle through the Michigan countryside.

Education

Simon Fraser University | Burnaby, BC, Canada| Ph.D. Chemistry | 2015 - 2021

UNC Greensboro | Greensboro, NC | B.S. Biochemistry | 2009-2015

Experience

Ometa Labs LLC | Director of Product | 2021 - present

Data Revenue GmbH | Mass Spectrometry Metabolomics Scientist and Science Writer | 2021-2022

Publications

(1)

Flores-Bocanegra, L.; Al Subeh, Z. Y.; Egan, J. M.; El-Elimat, T.; Raja, H. A.; Burdette, J. E.; Pearce, C. J.; Linington, R. G.; Oberlies, N. H. Dereplication of Fungal Metabolites by NMR-Based Compound Networking Using MADByTE. Journal of natural products 2022, 85 (3), 614–624.

(2)

Egan, J. M.; Santen, J. A. van; Liu, D. Y.; Linington, R. G. Development of an NMR-Based Platform for the Direct Structural Annotation of Complex Natural Products Mixtures. Journal of natural products 2021, 84 (4), 1044–1055.

(3)

Brown, A. R.; Ettefagh, K. A.; Todd, D. A.; Cole, P. S.; Egan, J. M.; Foil, D. H.; Lacey, E. P.; Cech, N. B. Bacterial Efflux Inhibitors Are Widely Distributed in Land Plants. Journal of Ethnopharmacology 2021, 267, 113533.

(4)

Van Santen, J. A.; Jacob, G.; Singh, A. L.; Aniebok, V.; Balunas, M. J.; Bunsko, D.; Neto, F. C.; Castaño-Espriu, L.; Chang, C.; Clark, T. N.; others. The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery. ACS central science 2019, 5 (11), 1824–1833.

(5)

McAlpine, J. B.; Chen, S.-N.; Kutateladze, A.; MacMillan, J. B.; Appendino, G.; Barison, A.; Beniddir, M. A.; Biavatti, M. W.; Bluml, S.; Boufridi, A.; others. The Value of Universally Available Raw NMR Data for Transparency, Reproducibility, and Integrity in Natural Product Research. Natural product reports 2019, 36 (1), 35–107.

(6)

Kellogg, J. J.; Todd, D. A.; Egan, J. M.; Raja, H. A.; Oberlies, N. H.; Kvalheim, O. M.; Cech, N. B. Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds. Journal of natural products 2016, 79 (2), 376–386.

(7)

Egan, J. M.; Kaur, A.; Raja, H. A.; Kellogg, J. J.; Oberlies, N. H.; Cech, N. B. Antimicrobial Fungal Endophytes from the Botanical Medicine Goldenseal (Hydrastis Canadensis). Phytochemistry letters 2016, 17, 219–225.

(8)

Brown, A. R.; Ettefagh, K. A.; Todd, D.; Cole, P. S.; Egan, J. M.; Foil, D. H.; Graf, T. N.; Schindler, B. D.; Kaatz, G. W.; Cech, N. B. A Mass Spectrometry-Based Assay for Improved Quantitative Measurements of Efflux Pump Inhibition. PLoS One 2015, 10 (5), e0124814.

(9)

Bussey III, R. O.; Kaur, A.; Todd, D. A.; Egan, J. M.; El-Elimat, T.; Graf, T. N.; Raja, H. A.; Oberlies, N. H.; Cech, N. B. Comparison of the Chemistry and Diversity of Endophytes Isolated from Wild-Harvested and Greenhouse-Cultivated Yerba Mansa (Anemopsis Californica). Phytochemistry letters 2015, 11, 202–208.